Naloxone Portal and Standing Order

The Naloxone Ordering Portal is currently active for existing accounts as of 4/1/2025. This program is now managed by the Minnesota Department of Human Services. As updates and resources become available, they will be provided here.

A Standing Order and Protocol are still required for some organizations to obtain and distribute opiate antagonists such as naloxone. This page will serve as a resource for organizations that require a standing order and protocol.

Standing Order and Protocol

The Standing Order and Protocol allows an organization to obtain, distribute, and administer naloxone. See example Standing Naloxone Order and Protocol (PDF). To get or renew your standing order complete the Standing Order Registration and Renewal Form. Use your organization’s business address, no PO boxes.

Contact information

For questions and technical assistance on the naloxone ordering portal, contact minnesota_naloxone_portal.dhs@state.mn.us. Note: Questions about your shipment should be sent to Narcan Direct at 844-462-7226 or narcandirect@ebsi.com.

Training Resources 

MDH School Health Team has gathered and reviewed several types of training materials and videos available through several state and national organizations. This list does not reflect endorsement of any specific training materials. Schools and other organizations will need to review and determine the training based on their policy, procedures, environment, and staff who are being trained. 

• MDH School Naloxone Toolkit
• Steve Rummler HOPE Network - Opioid Response Training 

Training Videos

• American Heart Association Opioid Education for Nonclinical Staff and Lay Responders (14 min)
• National School Nurse Association (NASN) Naloxone in Schools Toolkit
• NIH National Institute on Drug Abuse– How Naloxone Saves Lives in Opioid Overdose (2019) (5:30 min)
• Spanish translation (7 min)
• Steve Rummler HOPE Network Naloxone Demonstration Videos:
  • Intramuscular (IM) naloxone (6 mins)
  • Nasal naloxone/NARCAN (3 mins)
• California Department of Public Health – Administering Naloxone (2018) (11 min) 
  Note this resource uses California immunity laws – schools in Minnesota will need to cross reference Minnesota immunity laws: (604A.05 Good Samaritan Overdose Medical Assistance)
• Washington State’s stopoverdose.org 
  Note this resource uses Washington immunity laws – schools in Minnesota will need to cross reference Minnesota immunity laws (604A.05 Good Samaritan Overdose Medical Assistance)
• Wisconsin Department of Health Services Naloxone Training (2020) (12 min)  
  Note this resource uses Wisconsin immunity laws – schools in Minnesota will need to cross reference Minnesota immunity laws (604A.05 Good Samaritan Overdose Medical Assistance)

Manufacturer Resources and Instructions for Use

These manufacturers provide various types of resources that are specific to their products.

• Emergent Inc. NARCAN nasal spray 4 mg
• Narcan Instructions for Use (PDF) 
  This is written instruction for use of nasal administration.
• Email narcancustomerservice@ebsi.com to order a nasal training device.
• Hikma Specialty USA Inc. Kloxxado (naloxone HCl) nasal spray 8 mg
• Kloxxado Instructions for Use (PDF) 
  This is written instruction for use of nasal administration.
• Kloxxado Training Device 
  This is where you can order a nasal training device.
• TEVA naloxone hydrochloride nasal spray 4 mg
• TEVA Instructions for Use (PDF) 
  This is written instruction for use of nasal administration. 

FAQs

Q: Why do organizations need a Standing Order for naloxone?

A: The Standing Order is needed because naloxone is a prescription drug. The standing order not only allows groups to receive and possess it but also purchase, administer, and distribute the naloxone. 

Q: Why do schools need a Condition Specific Protocol for naloxone?

A: Naloxone is medication and schools should have direction on why, when, and how to give naloxone.

Q: How can organizations share extra naloxone kits?

A: We encourage you to share with other eligible groups outlined above, first responders, who are likely to respond to overdoses, as well as harm reduction groups in the state who provide naloxone to people most likely to overdose:

• Steve Rummler HOPE Network - Call 952-943-3937
• Rural AIDS Action Network (RAAN) - Call 320-257-3036
• Red Door Clinic - Call 612-543-5555
• Indigenous Peoples Task Force - Call 612-870-1723
• LSS StreetWorks Collaborative - Call 612-354-3345 or email street.works@lssmn.org
• Southside Harm Reduction Services - Text 612-615-9725

Q: Where can school nurses send questions about anything related to implementation of a naloxone program in their school?

A: Please send all inquiries to health.school.health@state.mn.us.