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Adolescent Immunization Rates

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Infectious Disease Epidemiology, Prevention and Control Division

651-201-5414

IDEPC Comment Form

Contact Info

Infectious Disease Epidemiology, Prevention and Control Division

651-201-5414

IDEPC Comment Form

About Adolescent Immunization Rates from NIS and MIIC

Detailed description of the differences between adolescent immunization rates from the National Immunization Survey (NIS) and the Minnesota Immunization Information Connection (MIIC).

Updated 10/2023

On this page:
Source
Who is assessed?
How are the rates generated?
Are there differences in how vaccine coverage is defined?
How valid are the rates?
How current are the rates?
Additional resources

Source

National Immunization Survey (NIS)	Minnesota Immunization Information Connection (MIIC)
Centers for Disease Control and Prevention (CDC).	Minnesota Department of Health (MDH).

Who is assessed?

NIS	MIIC
A random sample of U.S. adolescents ages 13 through 17 years. Sub-analysis available by age, state, some local areas, race/ethnicity, poverty status, and rural versus urban residence.	Minnesota adolescents ages 13 through 17 years in the MIIC immunization information system. Sub-analysis available by county and by other variables as requested and as available.

How are the rates generated?

NIS	MIIC
Minnesota rates are based on a surveyed sample of a few hundred Minnesota adolescents ages 13 through 17 years. The CDC contacts a random sample of families by phone to ask about their adolescents' vaccination histories and checks this information against providers' vaccination records.	Calculations are based on MIIC records of the approximately 400,000 Minnesota adolescents ages 13 through 17 years.

Are there differences in how vaccine coverage is defined?

There are differences in how the two data sources define coverage with Tdap, meningococcal, and HPV.

NIS	MIIC
Tdap coverage refers to the percentage of adolescents who have received 1 or more doses of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine at or after age 10 years.	Tdap coverage refers to the percentage of adolescents who have received 1 or more doses of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine at any age.
Meningococcal coverage refers to the percentage of adolescents who have received 1 or more doses of meningococcal conjugate (MenACWY) vaccine or meningococcal vaccine of unknown type.	Meningococcal coverage refers to the percentage of adolescents who have received 1 or more doses of meningococcal conjugate (MenACWY) vaccine.
HPV coverage refers to the percentage of adolescents who have received at least 1 dose of or are up-to-date (UTD) on human papillomavirus (HPV) vaccine. HPV UTD includes those with 3 or more doses or those with 2 doses when the first HPV vaccine dose was initiated prior to age 15 years and there were at least five months minus four days between the first and second doses.	HPV coverage refers to the percentage of adolescents who have received at least 1 dose of or are up-to-date (UTD) on human papillomavirus (HPV) vaccine. HPV UTD includes those with 3 or more doses and those with 2 or doses when the first HPV vaccine dose was initiated prior to age 15 years and there were at least five months minus four days between the first and second doses.

How valid are the rates?

NIS	MIIC
Minnesota rates are based on a surveyed sample of a few hundred Minnesota adolescents ages 13 through 17 years. Each estimate is accompanied by a "confidence interval," indicating 95 percent likelihood that the true rate falls within this range. Accuracy of the NIS coverage estimates are affected by: Survey design, Statistical adjustments used in calculating rates, and Parental and provider knowledge of adolescent vaccination history.	Calculations are based on approximately 400,000 Minnesota adolescents ages 13 through 17 years in MIIC. MIIC data may underestimate the actual percent of adolescents receiving vaccines because: Health care provider participation in MIIC is voluntary, MIIC may include adolescents who have moved and Cross border-state immunization data exchange is limited to Wisconsin, North Dakota, and Iowa. Although approximately 94 percent of Minnesota Vaccines for Children (MnVFC) health care providers routinely submit immunization data to MIIC, not all those who submit data report every administered vaccine or every historical vaccination reported by the patient. When an adolescent moves out of Minnesota, their MIIC record may not be updated, and the adolescent may still be included in the denominator used to calculate the proportion of adolescents receiving immunization.

NIS

MIIC

Minnesota rates are based on a surveyed sample of a few hundred Minnesota adolescents ages 13 through 17 years.
Each estimate is accompanied by a "confidence interval," indicating 95 percent likelihood that the true rate falls within this range.
Accuracy of the NIS coverage estimates are affected by:
- Survey design,
- Statistical adjustments used in calculating rates, and
- Parental and provider knowledge of adolescent vaccination history.

Calculations are based on approximately 400,000 Minnesota adolescents ages 13 through 17 years in MIIC.
MIIC data may underestimate the actual percent of adolescents receiving vaccines because:
- Health care provider participation in MIIC is voluntary,
- MIIC may include adolescents who have moved and
- Cross border-state immunization data exchange is limited to Wisconsin, North Dakota, and Iowa.
Although approximately 94 percent of Minnesota Vaccines for Children (MnVFC) health care providers routinely submit immunization data to MIIC, not all those who submit data report every administered vaccine or every historical vaccination reported by the patient.
When an adolescent moves out of Minnesota, their MIIC record may not be updated, and the adolescent may still be included in the denominator used to calculate the proportion of adolescents receiving immunization.

How current are the rates?

NIS	MIIC
NIS surveys are conducted throughout the calendar year, and each year's results are published in the fall of the following year. Rates reflect immunization practices 2 to 4 years in the past.	Annual MIIC rates are calculated based on records of adolescents ages 13 through 17 years as of July 1, 2022.

Additional resources

Adolescent Immunization Rates
Links to current Minnesota rates and rates over time from the NIS and MIIC.
Minnesota Immunization Information Connection (MIIC)
Information about the statewide immunization information system, MIIC.
TeenVaxView
NIS data for the nation, regions, states, and some local areas from the Centers for Disease Control and Prevention.
Minnesota Public Health Data Access: Immunizations
Interactive maps and tables showing MIIC-based immunization rates. Rates are available for single antigens and the childhood series by county and seven-county metro area ZIP codes.